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Your Position: Home > Cytokines & Growth Factors > Mouse CCL6 Protein,HEK293 expressed

Mouse CCL6 / C10 Protein

  • Synonym
    CCL6,SCYA6,C10,MRP-1
  • Source
    Mouse CCL6, His Tag (CC6-M5222) is expressed from human 293 cells (HEK293). It contains AA Gly 22 - Ala 116 (Accession # P27784).
    Predicted N-terminus: Gly 22
  • Molecular Characterization
    CCL6(Gly 22 - Ala 116) P27784

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 11.4 kDa. The protein migrates as 14 kDa under reducing (R) condition (SDS-PAGE).

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    No activity loss is observed after storage at:

    1. 4-8°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Mouse CCL6, His Tag (Cat. No. CC6-M5222) SDS-PAGE gel

Mouse CCL6, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

  • Background
    Chemokine (C-C motif) ligand 6 (CCL6), a member of the CC chemokine family, was initially identified as a transcript that is induced in bone marrow cells upon stimulation with GM­CSF. CCL6 has only been identified in rodents, A human homologue for mouse CCL6 has not been identified.  The mCCL6 cDNA encodes a 116 amino acid residue precursor protein with a hydrophobic signal peptide that is cleaved to yield a 95 amino acid residue mature protein. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, where it is strongly induced upon GM­CSF (Cat. # GMF-H4214) stimulation. Mouse CCL6 expression was also shown to be strongly induced by IL-4 (Cat. # IL4-H4218) in mouse macrophages and by cytokine IL­13 (Cat. # IL3-H4210) in mouse lung. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.
  • References
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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