This is the new website for acrobiosystems.com. We would love to hear what you think of it - please send feedback

Welcome to ACROBiosystems

0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > Immune Checkpoint Proteins > Human CD48 /BCM1 /SLAMF2 Protein

Human CD48 / SLAMF2 Protein

  • Synonym
    CD48,BCM1,SLAMF2,BLAST1,BLAST,BLAST1,MEM-102,TCT.1,BCM-1,SLAMF-2,BLAST-1
  • Source
    Human CD48, His Tag (BC1-H5226) is expressed from human 293 cells (HEK293). It contains AA Gln 27 - Ser 220 (Accession # AAH16182).
    Predicted N-terminus: Gln 27
  • Molecular Characterization
    CD48(Gln 27  - Ser 220) AAH16182

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 23.2 kDa. The protein migrates as 38-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    No activity loss is observed after storage at:

    1. 4-8°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human CD48, His Tag (Cat. No. BC1-H5226) SDS-PAGE gel

Human CD48, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity
Human CD48, His TagHuman CD48, His Tag (Cat. No. BC1-H5226) ELISA bioactivity

Immobilized Human 2B4, Fc Tag (Cat. No. 2B4-H5255) at 5 μg/mL (100 μL/well) can bind Human CD48, His Tag (Cat. No. BC1-H5226) with a linear range of 0.156-2.5 μg/mL (QC tested).

  • Background
    CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.
  • References
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

Comments (0)

Order Details

Price(USD) : $250.00

Inventory : In-stock

Price(USD) : $1500.00

Inventory : In-stock

Datasheet & Documentation

Contact Us

+1  800-810-0816 (US)
+86 400-682-2521 (AP)

Questions & Comments

This web search service is supported by Google Inc.