Browse Products By Molecule:

This web search service is supported by Google Inc.

Products --> Bio-Markers & CD Antigens

Human Syndecan-1 Protein  pdf  pdf  pdf


Cat-Pack Size Price(USD) Qty Inventory Order
Quote for bulk   Worldwide Shipping & Payment
SD1-H5228-100ug
    $250.00
SD1-H5228-1mg (500ug x 2)
    $1500.00
In-Stock
Place Purchase Orders


Synonym

SDC1,Syndecan-1,CD138,SYND1,SDC

Source

Human Syndecan-1, His Tag (SD1-H5228) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Gly 254 (Accession # AAH08765).

Predicted N-terminus: Gln 23

Molecular Characterization

Syndecan-1(Gln 23 - Gly 254)AAH08765
Poly-his

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 24.7 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Purity

>92% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Storage

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

No activity loss is observed after storage at:

  1. 4-8°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

SDS-PAGE

Human Syndecan-1, His Tag (Cat. No. SD1-H5228) SDS-PAGE gel

Human Syndecan-1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%.

 

Background

Syndecan-1 (SYND1 or SDC1) is also known as CD antigen CD138, is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 / SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood.

References

Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

Related Products

Questions & Comments