DPPII,QPP,DPP7,DPP2,Dipeptidyl peptidase 2,Dipeptidyl aminopeptidase II
Human DPPII / QPP / DPP7 Protein (Human DPPII, His Tag) Gly 22 - Leu 492 (Accession # AAH11907) was produced in human 293 cells (HEK293) at ACROBiosystems.
Human DPPII, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 53 kDa. The predicted N-terminus is Gly 22. The reducing (R) protein migrates as 60-66 kDa in SDS-PAGE due to glycosylation.
Less than 1.0 EU per μg by the LAL method.
>95% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH 7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization.
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See Certificate of Analysis for reconstitution instructions and specific concentrations.
Avoid repeated freeze-thaw cycles.
No activity loss was observed after storage at:
In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C).
Dipeptidyl peptidase 2 (DPP2 or DPP II) is also known as Dipeptidyl peptidase 7 (DPP7), Quiescent cell proline dipeptidase (QPP), which belongs to the peptidase S28 family. DPP7 / DPP2 is detected in seminal plasma (at protein level). When the pH is 5.5, Dipeptidyl peptidase 2 display a optimum catalytic activity. DPP7 has low activity at pH 7 and is inactive at pH 8. DPP7 plays an important role in the degradation of some oligopeptides.
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