DPPII,QPP,DPP7,DPP2,Dipeptidyl peptidase 2,Dipeptidyl aminopeptidase II
Human DPPII, His Tag (DP7-H5222) is expressed from human 293 cells (HEK293). It contains AA Gly 22 - Leu 492 (Accession # AAH11907).
Predicted N-terminus: Gly 22
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 53 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Less than 1.0 EU per μg by the LAL method.
>95% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH 7.5. Normally trehalose is added as protectant before lyophilization.
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Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
No activity loss is observed after storage at:
- 4-8°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
Human DPPII, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Dipeptidyl peptidase 2 (DPP2 or DPP II) is also known as Dipeptidyl peptidase 7 (DPP7), Quiescent cell proline dipeptidase (QPP), which belongs to the peptidase S28 family. DPP7 / DPP2 is detected in seminal plasma (at protein level). When the pH is 5.5, Dipeptidyl peptidase 2 display a optimum catalytic activity. DPP7 has low activity at pH 7 and is inactive at pH 8. DPP7 plays an important role in the degradation of some oligopeptides.
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