Human OMgp, His Tag (OMG-H5228) is expressed from human 293 cells (HEK293). It contains AA Ile 25 - Asn 420 (Accession # AAH18050).
Predicted N-terminus: Ile 25
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 45.5 kDa. The protein migrates as 90-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Less than 1.0 EU per μg by the LAL method.
>92% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally trehalose is added as protectant before lyophilization.
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Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
No activity loss is observed after storage at:
- 4-8°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
Human OMgp, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%.
Oligodendrocyte-myelin glycoprotein (OMG or OMGP), is a cell membrane protein which contains eight LRR (leucine-rich) repeats and one LRRNT domain. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP play roles in both the developing and adult central nervous system. OMG / OMGP may also be involved in the formation and maintenance of myelin sheaths.
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