Recombinant Human OMG /OMGP Protein (rh OMG / OMGP) Ile 25 - Asn 420 (Accession # AAH18050) was produced in human 293 cells (HEK293) at ACRObiosystems.
rh OMG / OMGP, fused with polyhistidine tag at the C-terminus, has a calculated MW of 45.5 kDa. The predicted N-terminus is Ile 25. DTT-reduced Protein migrates as 90-120 kDa due to glycosylation.
Less than 1.0 EU per μg of the rh OMG / OMGP by the LAL method.
>92% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
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See Certificate of Analysis for details of reconstitution instruction and specific concentration.
Avoid repeated freeze-thaw cycles.
No activity loss was observed after storage at:
In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC).
Oligodendrocyte-myelin glycoprotein (OMG or OMGP), is a cell membrane protein which contains eight LRR (leucine-rich) repeats and one LRRNT domain. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP play roles in both the developing and adult central nervous system. OMG / OMGP may also be involved in the formation and maintenance of myelin sheaths.
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