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Human OMgp / OMG Protein  pdf  pdf  pdf


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OMG-H5228-100ug
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OMG-H5228-1mg (250ug x 4)
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Synonym

OMG,OMGP

Source

Human OMgp, His Tag (OMG-H5228) is expressed from human 293 cells (HEK293). It contains AA Ile 25 - Asn 420 (Accession # AAH18050).

Predicted N-terminus: Ile 25

Molecular Characterization

OMgp(Ile 25 - Asn 420)AAH18050
Poly-his

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 45.5 kDa. The protein migrates as 90-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Purity

>92% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Storage

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

No activity loss is observed after storage at:

  1. 4-8°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

SDS-PAGE

Human OMgp, His Tag (Cat. No. OMG-H5228) SDS-PAGE gel

Human OMgp, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%.

 

Background

Oligodendrocyte-myelin glycoprotein (OMG or OMGP), is a cell membrane protein which contains eight LRR (leucine-rich) repeats and one LRRNT domain. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP play roles in both the developing and adult central nervous system. OMG / OMGP may also be involved in the formation and maintenance of myelin sheaths.

References

Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.


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