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FcRn (FCGRT & B2M) Molecule Synonym Name

FcRn,FCGRT & B2M

FcRn (FCGRT & B2M) Protein Products

Cat No Species Product Description
FCM-C5284Cynomolgus / RhesusCynomolgus / Rhesus macaque FcRn / FCGRT & B2M Heterodimer Protein
FCM-C82W5Cynomolgus / RhesusBiotinylated Cynomolgus / Rhesus macaque FcRn / FCGRT & B2M, Avi Tag (Avitag?)
FCM-H5286HumanHuman FcRn / FCGRT & B2M Heterodimer Protein
FCM-H8286HumanBiotinylated Human FcRn / FCGRT & B2M, ultra sensitivity (primary amine labeling)
FCM-H82W4HumanBiotinylated Human FcRn / FCGRT & B2M, Avi Tag (Avitag?)
FCM-M52W2MouseMouse FcRn / FCGRT & B2M Heterodimer Protein
FCM-M82W6MouseBiotinylated Mouse FcRn / FCGRT & B2M, Avi Tag (Avitag?)
FCM-P5280PorcinePorcine FcRn / FCGRT & B2M Heterodimer Protein
FCM-R5287RatRat FcRn / FCGRT & B2M Heterodimer Protein
FCM-R82W7RatBiotinylated Rat FcRn / FCGRT & B2M, Avi Tag (Avitag?)

FcRn (FCGRT & B2M) Molecule Background

FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

Reference

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