IL7Ra / CD127 Molecule
IL-7 R alpha / CD127 Molecule Synonym Name
IL-7 R alpha / CD127 Protein Products
|Cat No||Species||Product Description|
|ILA-H5258||Human||Human IL-7 R alpha / CD127 Protein, Fc Tag|
|IL7-H82F8||Human||Biotinylated Human IL-7 R alpha / CD127 Protein, Fc Tag, Avi Tag (Avitag?)|
IL-7 R alpha / CD127 Molecule Background
Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.
- (1) Noguchi M., et al., 1994, Science 262 (5141): 1877–80.
- (2) Kroemer RT., et al., 1997, Protein Eng. 9 (12): 1135–42.
- (3) McElroy C.A., et al., 2009, Structure 17:54-65.