IL27RA / TCCR Molecule
IL-27 Ra / TCCR Molecule Synonym Name
IL-27 Ra / TCCR Protein Products
|Cat No||Species||Product Description|
|ILA-H5254||Human||Human IL-27 Ra / TCCR Protein, Fc Tag|
IL-27 Ra / TCCR Molecule Background
Interleukin-27 receptor subunit alpha ( IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily. IL27RA contains three fibronectin type-III domains. IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27. IL27RA involved in the regulation of Th1-type immune responses. IL27RA also appears to be involved in innate defense mechanisms.
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- (3) Pflanz S., et al., 2004, J. Immunol. 172:2225-2231.