CDH6 / KCAD Molecule
Cadherin-6 Molecule Synonym Name
Cadherin-6 Protein Products
|Cat No||Species||Product Description|
|CA6-H5229||Human||Human Cadherin-6 / KCAD / CDH6 Protein|
Cadherin-6 Molecule Background
Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.
- (1) Suzuki S., et al., 1991, Cell Regul. 2:261-270.
- (2) MacCalman CD., et al., 1998, Am. J. Reprod. Immunol. 39 (2): 96–107.