CD48 / SLAMF2 Molecule
CD48 / SLAMF2 Molecule Synonym Name
CD48 / SLAMF2 Protein Products
|Cat No||Species||Product Description|
|BC1-H5226||Human||Human CD48 / SLAMF2 Protein|
CD48 / SLAMF2 Molecule Background
CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.
- (1) Korinek V., et al., 1991, Immunogenetics 33:108-112.
- (2) Wollscheid B., et al., 2009, Nat. Biotechnol. 27:378-386.