CRABP2 Molecule Synonym Name
CRABP2 Protein Products
|Cat No||Species||Product Description|
|CR2-H5140||Human||Human CRABP2 Protein|
CRABP2 Molecule Background
Cellular retinoic acid-binding protein 2 (CRABP2) is also known as cellular retinoic acid-binding protein II (CRABP-II), which is a member of the calycin superfamily and fatty-acid binding protein (FABP) family. CRABP2 is structurally similar to CRABP1, but CRABP2 has a lower affinity for retinoic acid (RA). CRABP2 is associated with cells that produce large amounts of retinoic acid and may play a role in mediating the effects of retinoic acid in the cell. Furthermore, the inducibility of the CRABP2 gene suggests that this isoform is important in retinoic acid-mediated regulation of human skin growth, differentiation and development.
- (1) Astroem A., et al., 1991, J. Biol. Chem. 266:17662-17666.
- (2) Budhu A.S., et al., 2002, Mol. Cell. Biol. 22:2632-2641.
- (3) Majumdar A., et al., 2011, J. Biol. Chem. 286:42749-42757.