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DNAM-1 / CD226 Molecule  


DNAM-1 / CD226 Molecule Synonym Name

DNAM1,CD226,PTA1

DNAM-1 / CD226 Protein Products

Cat No Species Product Description
DN1-H5257HumanHuman DNAM-1 / CD226 Protein, Fc Tag
DN1-H52H6HumanHuman DNAM-1 / CD226 Protein
DN1-H82F9HumanBiotinylated Human DNAM-1 / CD226 Protein, Fc Tag, Avi Tag (Avitag?)

DNAM-1 / CD226 Molecule Background

DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

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