Glypican 3 / GPC3 Molecule
Glypican 3 / GPC3 Molecule Synonym Name
Glypican 3 / GPC3 Protein Products
|Cat No||Species||Product Description|
|GP3-C5256||Cynomolgus||Cynomolgus Glypican 3 / GPC3 Protein, Fc Tag|
|GP3-H5223||Human||Human Glypican 3 / GPC3 Protein, low endotoxin|
|GP3-H5258||Human||Human Glypican 3 / GPC3 Protein, Fc Tag, low endotoxin|
|GP3-M5254||Mouse||Mouse Glypican 3 / GPC3 Protein, Fc Tag|
|GP3-C5225||Cynomolgus||Cynomolgus Glypican 3 / GPC3 Protein, His Tag|
Glypican 3 / GPC3 Molecule Background
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
- (1) Davoodi J., et al., 2007, Proteomics 7:2300-2310.
- (2) Veugelers M., et al., 2000, Hum. Mol. Genet. 9:1321-1328.