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Your Position: Home > HABP1

HABP1

Brief Information

Name:HLA-DR antigens-associated invariant chain
Target Synonym:CLIP,CD74,Ia antigen-associated invariant chain,CD74 Molecule,CD74 Antigen (Invariant Polypeptide Of Major Histocompatibility Complex, Class II Antigen-Associated),CD74 Molecule, Major Histocompatibility Complex, Class II Invariant Chain,HLA-DR Antigens-Associated Invariant Chain,Ia-Associated Invariant Chain,MHC HLA-DR Gamma Chain,HLA-DR-Gamma,DHLAG,P33,CD74 Antigen,Ia-GAMMA,HLADG,II,Gamma Chain Of Class II Antigens,HLA Class II Histocompatibility Antigen Gamma Chain
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 2 Clinical

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Cat. No. Species Product Description Structure Purity Feature
C1P-H5122 Human Human HABP1 / C1QBP Protein, His Tag
C1P-H5122-structure
C1P-H5122-sds
ACRO Quality

Synonym Name

C1QBP,GC1QBP,HABP1,SF2P32,p33

Background

Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP), a member of the MAM33 family, is also known as ASF/SF2-associated protein p32, glycoprotein gC1qBP (C1qBP), mitochondrial matrix protein p32 and hyaluronan-binding protein 1, which is a homotrimer that contains three monomers forming a donut-shaped structure with an unusually asymmetric charge distribution on the surface. C1QBP associates with C1r and C1s in order to yield the first component of the serum complement system. C1QBP has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. Furthermore, C1QBP has been shown to interact with Protein kinase D1, BAT2, PRKCD, PKC alpha and Protein kinase M¦Æ .

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Influenza A M1 vaccine (Pascal Biosciences) Phase 1 Clinical Pascal Biosciences Influenza A virus infections Details
Bezetabart debotansine BN-301; SP7675; STRO-001; SP-7675 Phase 2 Clinical Bionova Pharmaceuticals (Shanghai) Ltd, Sutro Biopharma Inc Hematologic Neoplasms; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Multiple Myeloma; Lymphoma, Mantle-Cell; Lymphoma, Follicular; Lymphoma, Non-Hodgkin Details

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