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>IL-1 RAcP / IL-1 R3 Molecule
|Cat No||Species||Product Description|
|ILP-H5225||Human||Human IL-1 RAcP / IL-1 R3 Protein|
|ILP-H5256||Human||Human IL-1 RAcP / IL-1 R3 Protein, Fc Tag|
Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
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