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Browse By Molecule Name --->Mannose-binding lectin Molecule

Mannose-binding lectin Molecule  


Mannose-binding lectin Molecule Synonym Name

MBL,MBL2,MBP1,MBP-C,Collectin-1,COLEC1,HSMBPC,MBL2D,MBPD

Mannose-binding lectin Protein Products

Cat No Species Product Description
MBL-H5220HumanHuman MBL Protein

Mannose-binding lectin Molecule Background

Mannose-binding lectin (MBL) is also known as mannose-binding protein, mannan-binding protein (MBP), Mannose-binding protein C, Collectin-1 (COLEC1), MBL2, which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA.

Reference

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