SIRP gamma / CD172g Molecule
SIRP gamma / CD172g Molecule Synonym Name
SIRP gamma / CD172g Protein Products
|Cat No||Species||Product Description|
|SIG-H5253||Human||Human SIRP gamma / CD172g Protein, Fc Tag|
SIRP gamma / CD172g Molecule Background
Signal-regulatory protein gamma (SIRPG or SIRP-gamma) is also known as CD172 antigen-like family member B (CD172g), Signal-regulatory protein beta-2 (SIRPB2), is a single-pass type I membrane protein. SIRPG is expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. SIRPG interacts with CD47. On binding with CD47, CD172g mediates cell-cell adhesion.
- (1) Ichigotani Y., et al., 2000, J. Hum. Genet. 45:378-382.
- (2) Piccio L., et al., 2005, Blood 105:2421-2427.