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B18R Molecule  


B18R Molecule Synonym Name

B18R

B18R Protein Products

Cat No Species Product Description
B1R-H52H6Vaccinia VirusVaccinia Virus B18R Protein

B18R Molecule Background

B18R is a type I interferon (IFN)-binding protein and it is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus, which contains two Ig-like C2-type domains and one Ig-like V-type domain. B18R exists in a soluble and a membrane-bound form. As a type I IFN receptor, B18R counteracts the antiviral effects of host IFN-alpha/beta. Also, B18R acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor.

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