CD163 Molecule Synonym Name
CD163 Protein Products
|Cat No||Species||Product Description|
|CD3-H52E8||Human||Human CD163 Protein|
CD163 Molecule Background
Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is also known as hemoglobin scavenger receptor, which is a scavenger receptor for the hemoglobin-haptoglobin complex. CD163 has also been shown to mark cells of monocyte/macrophage lineage. A soluble form of the receptor exists in plasma, commonly denoted sCD163. sCD163 is generated by ectodomain shedding of the membrane bound receptor. sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher's disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.
- (1) Law S.K.A., et al., 1993, Eur. J. Immunol. 23:2320-2325.
- (2) Matsushita N., et al., 2002, Clin. Exp. Immunol. 130:156-161.
- (3) Ritter M., et al., 2001, Eur. J. Immunol. 31:999-1009.