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Browse By Molecule Name --->B7-H3 / CD276 Molecule

B7-H3 / CD276 Molecule  

B7-H3 / CD276 Molecule Synonym Name

B7-H3,CD276,B7 homolog 3

B7-H3 / CD276 Protein Products

Cat No Species Product Description
B73-H5253 Human Human B7-H3 / CD276 Protein, Fc Tag
B73-H52E2 Human Human B7-H3 / CD276 Protein
B73-M5255 Mouse Mouse B7-H3 / CD276 Protein, Fc Tag
B73-M52H4 Mouse Mouse B7-H3 / CD276 Protein
B73-H82E6 Human Biotinylated Human B7-H3 / CD276 Protein, His Tag & Avi Tag (Avitag™)

B7-H3 / CD276 Molecule Background

B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.


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