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Transferrin R2 / TFR2 Molecule  


Transferrin R2 / TFR2 Molecule Synonym Name

Transferrin R2,TFR2

Transferrin R2 / TFR2 Protein Products

Cat No Species Product Description
TF2-M5269MouseMouse Transferrin R2 Protein, mouse IgG1 Fc Tag

Transferrin R2 / TFR2 Molecule Background

Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III. Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.

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