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CX3CL1 / Fractalkine Molecule  


CX3CL1 / Fractalkine Molecule Synonym Name

CX3CL1,Fractalkine

CX3CL1 / Fractalkine Protein Products

Cat No Species Product Description
CX1-H5221HumanHuman CX3CL1 / Fractalkine Protein
CX1-H8221HumanBiotinylated Human CX3CL1, ultra sensitivity (primary amine labeling)

CX3CL1 / Fractalkine Molecule Background

Fractalkine is also known as C-X3-C motif chemokine 1 (CX3CL1) and neurotactin. Fractalkine is a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. Fractalkine is found commonly throughout the brain, particularly in neural cells, and its receptor is known to be present on microglial cells. It has also been found to be essential for microglial cell migration. CX3CL1 is also up-regulated in the hippocampus during a brief temporal window following spatial learning, the purpose of which may be to regulate glutamate-mediated neurotransmission tone. This indicates a possible role for the chemokine in the protective plasticity process of synaptic scaling.

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