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Your Position: Home > Insights > GPC3 proteins from ACROBiosystems
GPC3 proteins from ACROBiosystems
Release time: 2017-11-19 Source: ACROBiosystems Read: 578

Glypican-3 (GPC3), a 70 kDa surface-bound proteoglycan, is an important biomarker of hepatocellular carcinoma (HCC) (Nakatsura et al., 2003). In the disease tissue, GPC3 is overexpressed at both gene and protein levels. It regulates multiple downstream signaling cascade, and by doing so stimulates macrophage engagement and promotes epithelial-mesenchymal transition (EMT). Therefore, GPC3 has been extensively investigated as a molecule of interest for molecular imaging and targeted therapy.

ACROBiosystems provides a comprehensive panel of human GPC3 proteins, including both His-tagged GPC3 (Cat. No. GP3-H5223) and Fc-fusion GPC3 (Cat. No. GP3-H5258). In addition, we also offer Cynomolgus GPC3 and Mouse GPC3 proteins in His-tagged and Fc-tagged format. The pre-biotinylated GPC3 protein (Avitag™) will come soon.

The interaction between GPC3 and growth factors (Zhou et al., 2017).

GPC3 Highlight


Human Glypican 3 / GPC3, Fc Tag, low endotoxin on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.


Immobilized Human FGF basic, Tag Free (Cat. No. BFF-H4117) at 2 μg/mL (100 μL/well) can bind Human Glypican 3, Fc Tag (Cat. No. GP3-H5258) with a linear range of 0.48-7.8 ng/mL (QC tested).

GPC3 product list

Cat. No.SpeciesProduct Descriptio0n
Coming soonHumanBiotinylated Human Glypican 3 / GPC3 Protein (Avitag )
GP3-H5258HumanHuman Glypican 3 / GPC3 Protein, Fc Tag,low endotoxin
GP3-H5223HumanHuman Glypican 3 / GPC3 Protein,low endotoxin
GP3-C5256CynomolgusCynomolgus Glypican 3 / GPC3 Protein,Fc Tag
GP3-C5225CynomolgusCynomolgus Glypican 3 / GPC3 Protein
GP3-M5254MouseMouse Glypican 3 / GPC3 Protein, Fc Tag
GP3-M52H3MouseMouse Glypican 3 / GPC3 Protein
> Click to view all GPC3 products

Related products

MoleculeCat. No.Product Descriptio0n
TGF-Beta 1TG1-H524xHuman Latent TGF-beta 1 / TGFB1 Protein
TGF-Beta 1TG1-H4212Human TGF-Beta 1 / TGFB1 Protein
TGF-Beta 1LAP-H5245Human LAP (TGF-beta 1) Protein
TGF-Beta 1TG2-H5252Human TGF-beta RII / TGFBR2 Protein, Fc Tag
BMP-2BM2-H4117Human BMP-2 Protein, Tag Free
BMPR-IAAL3-H5228Human BMPR-IA / ALK-3 Protein
BMPR-IAAL3-H5259Human BMPR-IA / ALK-3 Protein, Fc Tag


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