This is the new website for acrobiosystems.com. We would love to hear what you think of it - please send feedback
>CD16A / FCGR3A Molecule
|Cat No||Species||Product Description|
|CD8-H52H4||Human||Human FCGR3A / CD16a (V176) Protein|
|CDA-H5220||Human||Human FCGR3A / CD16a (F176) Protein|
|CDA-H82E8||Human||Biotinylated Human Fc gamma RIIIA / CD16a (F176), Avi Tag (Avitag™)|
|CDA-H82E9||Human||Biotinylated Human Fc gamma RIIIA / CD16a (V176), Avi Tag (Avitag™)|
|CDA-M52H8||Mouse||Mouse FCGR3A / CD16a Protein|
CD16 is a low affinity Fc receptor, and has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b). These receptors bind to the Fc portion of IgG antibodies. CD16 encoded by two different highly homologous genes in a cell type-specific manner.CD16 is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16a antigen is also known as Low affinity immunoglobulin gamma Fc region receptor III-A, Fc-gamma RIII-alpha. CD16b is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas CD16a is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placentaltrophoblasts.CD16a is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody?dependent cytotoxicity and clearance of immune complexes. Aberrant expression or mutations of CD16a is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia.
This web search service is supported by Google Inc.