|Cat No||Species||Product Description|
|MSN-H5222||Human||Human Mesothelin / MSLN (37-286) Protein|
|MSN-H5223||Human||Human Mesothelin / MSLN (296-580) Protein|
|MSN-H526x||Human||Human Mesothelin / MSLN (296-580) Protein, Fc Tag|
|MSN-H8223||Human||Biotinylated Human Mesothelin / MSLN (296-580), ultra sensitivity (primary amine labeling)|
|MSN-H826x||Human||Biotinylated Human Mesothelin / MSLN (296-580), Fc Tag, ultra sensitivity (primary amine labeling)|
|MSN-H82E9||Human||Biotinylated Human Mesothelin / MSLN (296-580), His Tag & Avi Tag (Avitag™)|
Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
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