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Your Position: Home > CD6


Brief Information

Name:T-cell differentiation antigen CD6
Target Synonym:T12,CD6,CD6 Molecule,TP120,T-Cell Differentiation Antigen CD6,CD6 Antigen
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
CD6-H52H7 Human Human CD6 / TP120 Protein, His Tag

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CD6 (Cluster of Differentiation 6) is a cell surface glycoprotein that is involved in T cell activation and a member of the scavenger receptor cysteine rich protein superfamily (SRCRSF). CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. The majority of peripheral blood T cells, a subset of B cells, and a subset of neuronal cells express CD6. CD6 appears to play a role as both a costimulatory molecule in T cell activation and as an adhesion receptor. Studies demonstrating a mitogenic effect for T cells with some CD6 specific monoclonal antibodies, in conjunction with either accessory cells or PMA and anti-CD2 mAb, support the concept of CD6 as a co stimulatory molecule.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Itolizumab Bmab-600; T-1-h; EQ-001; T-1-hT; h-T1 Approved Biocon, Center Of Molecular Immunology, Biotech Pharmaceuticals Co Ltd Alzumab India Plaque psoriasis Biocon 2013-01-01 Graft vs Host Disease; Lupus Erythematosus, Cutaneous; Lupus Nephritis; Coronavirus Infections; Psoriasis; Asthma; Plaque psoriasis Details

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