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Brief Information

Name:Thyroid stimulating hormone receptor
Target Synonym:TSHR,Thyroid Stimulating Hormone Receptor,LGR3,Thyroid-Stimulating Hormone Receptor,Seven Transmembrane Helix Receptor,Thyrotropin Receptor-I, HTSHR-I,Thyrotropin Receptor,TSH Receptor,HTSHR-I,TSH-R,Receptors, Thyrotropin,CHNG1
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:3
Lastest Research Phase:Approved

Synonym Name



Thyroid-stimulating hormone receptor (TSHR) is also known as Thyrotropin receptor and LGR3. TSHR is glycosylated receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

Clinical and Translational Updates

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