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Your Position: Home > TSHR

TSHR

TSHR Molecule Information

Name:Thyroid stimulating hormone receptor
Target Synonym:TSHR?Thyroid Stimulating Hormone Receptor?LGR3?Thyroid-Stimulating Hormone Receptor?Seven Transmembrane Helix Receptor?Thyrotropin Receptor-I? HTSHR-I?Thyrotropin Receptor?TSH Receptor?HTSHR-I?TSH-R?Receptors? Thyrotropin?CHNG1

Number of Launched Drugs:1
Number of Drugs in Clinical Trials:3
Lastest Research Phase:Approved

TSHR Molecule Synonym Name

TSHR,TSH-R,LGR3,TSH R

TSHR Molecule Background

Thyroid-stimulating hormone receptor (TSHR) is also known as Thyrotropin receptor and LGR3. TSHR is glycosylated receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

TSHR References

TSHR Public Drug Information

Name	Research Code	Research Phase	Company	First Brand Name	First Approved Country	First Indication	First Approved Company	First Approved Date	Indications	Clinical Trials
Thyrotropin alfa	rh-TSH; MRrhTSH; rhTSH-M	Approved	Genzyme Corp	Thyrogen	Japan	Thyroid Neoplasms	s:20:"Genzyme Corp, Sanofi";	1998-11-30	Thyroid Neoplasms; Diagnostic agents	Details

TSHR Clinical Drug Information

Name	Research Code	Research Phase	Company	Indications	Clinical Trials
Recombinant human thyrotropin (Zelgen Biosciences)		Phase 2 Clinical	Suzhou Zelgen Biosciences Co Ltd	Thyroid Neoplasms	Details
ICTCAR023	ICTCAR023	Phase 1 Clinical	Innovative Cellular Therapeutics Co Ltd	Thyroid Neoplasms	Details
Anti-thyroid stimulating hormone receptor chimeric antigen receptor T cell therapy (Innovative Cellular Therapeutics)	ICTCAT-023	Phase 2 Clinical	Innovative Cellular Therapeutics Co Ltd	Thyroid Neoplasms	Details