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CCL19

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Cat. No. Species Product Description Structure Purity Feature
CC9-H5215 Human ActiveMax® Human CCL19 / MIP-3 beta Protein, Tag Free (HPLC verified)
CC9-H5215-structure
CC9-H5215-sds
CC9-H5215-hplc

Part of Bioactivity data

CC9-H5215-MALS-HPLC
ActiveMax® Human CCL19, Tag Free (Cat. No. ) HPLC images

The purity of ActiveMax® Human CCL19, Tag Free (Cat. No. CC9-H5215) was greater than 95% as determined by SEC-HPLC.

Synonym Name

CCL19,MIP-3 beta,MIP-3-beta,ELC,MIP3B,SCYA19,EBI1 ligand chemokine

Background

C-C motif chemokine 19(CCL19) is as known as CK beta-11, ELC, MIP3B and SCYA19. May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

Clinical and Translational Updates

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