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Papain-like Protease

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Cat. No. Species Product Description Structure Purity Feature
PAE-C5148 SARS-CoV-2 SARS-CoV-2 (COVID-19) Papain-like Protease Protein, His Tag (active enzyme)
PAE-C5148-structure
PAE-C5148-sds

Papain-like Protease Molecule Synonym Name

Papain-like Protease,Replicase polyprotein 1a,ORF1a polyprotein,pp1a,1a,PL-PRO,Plpro

Papain-like Protease Molecule Background

New coronavirus is a single-stranded RNA positive-strand envelope type B coronavirus. Similar to the other two coronaviruses that cause SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome), its genome encodes non-structural, structural, and accessory proteins. Non-structural proteins include 3-chymotrypsin-like protease (3CLpro), papain-like protease, helicase, and RNA-dependent RNA polymerase (RNA -dependent RNA polymerase (RdRp). Structural proteins include spike glycoproteins. Papain in coronavirus is the same as 3CLpro. This enzyme operates on no less than 11 cleavage sites on the large polyprotein 1ab. Processing of polyproteins translated from viral RNA is essential. Therefore, press this The activity of this enzyme will prevent virus imitation.

Papain-like Protease References

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