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Your Position: Home > CD8 alpha & beta

CD8 alpha & beta

Brief Information

Name:T-cell surface glycoprotein CD8 beta chain
Target Synonym:CD8b,CD8b Molecule
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:

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Part of Bioactivity data

CDA-H52W5-ELISA
 CD8 alpha & beta ELISA

Immobilized Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free (Cat. No. CDA-H52W5) at 1 μg/mL (100 μL/well) can bind Anti-CD8 alpha Antibody, Mouse IgG2a (clone: OKT8) with a linear range of 0.2-5 ng/mL (QC tested).

CDA-H82W7-MALS-HPLC
CD8 alpha & beta MALS images

The purity of Biotinylated Human CD8A&CD8B Heterodimer Protein, His,Avitag&Tag Free (Cat. No. CDA-H82W7) is more than 90% and the molecular weight of this protein is around 50-65 kDa verified by SEC-MALS.

CD8 alpha & beta Molecule Synonym Name

CD8 alpha & beta,CD8A & CD8B

CD8 alpha & beta Molecule Background

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.

CD8 alpha & beta References

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