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CD8 alpha & beta

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CD8 alpha & beta Part of Bioactivity data

CDA-HF2W4-ELISA
FITC-Labeled Human CD8A&CD8B Heterodimer Protein, His Tag&Tag FreeFITC-Labeled Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free (Cat. No. CDA-HF2W4) ELISA bioactivity

Immobilized Anti-CD8 alpha Antibody, Mouse IgG2a (clone: OKT8) at 1 μg/mL (100 μL/well) can bind FITC-Labeled Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free (Cat. No. CDA-HF2W4) with a linear range of 0.625-2.5 μg/mL (QC tested).

CDA-H52W5-MALS-HPLC
Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free (Cat. No. ) MALS images

The purity of Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free (Cat. No. CDA-H52W5) was more than 85% and the molecular weight of this protein is around 55-65 kDa verified by SEC-MALS.

Bioactivity-ELISA
Human CD8A&CD8B Heterodimer Protein, His Tag&Tag FreeHuman CD8A&CD8B Heterodimer Protein, His Tag&Tag Free (Cat. No. CDA-H52W5) ELISA bioactivity

Immobilized Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free (Cat. No. CDA-H52W5) at 1 μg/mL (100 μL/well) can bind Anti-CD8 alpha Antibody, Mouse IgG2a (clone: OKT8) with a linear range of 0.2-5 ng/mL (QC tested).

CD8 alpha & beta Molecule Synonym Name

CD8 alpha & beta,CD8A & CD8B

CD8 alpha & beta Molecule Background

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.

CD8 alpha & beta References

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