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DNP

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Cat. No. Species Product Description Structure Purity Feature
DNP-PM1 Mouse PE-Labeled Monoclonal Anti-DNP antibody, Mouse IgG1 Isotype Control (Site-specific conjugation)
DNP-FM1A1 Mouse FITC-Labeled Monoclonal Anti-DNP antibody, Mouse IgG1 Isotype Control
DNP-M915 Human Monoclonal Anti-DNP antibody, Human IgG3 Isotype Control (carrier free)
DNP-M915-sds
DNP-M915-elisa_1
DNP-BM190 Mouse Biotinylated Monoclonal Anti-DNP antibody, Mouse IgG1 Avitag™ Isotype Control
DNP-M1A1 Mouse Monoclonal Anti-DNP antibody, Mouse IgG1 Isotype Control
DNP-BM2 Human Biotinylated Monoclonal Anti-DNP antibody, Human IgG1 Isotype Control (carrier free, MALS verified)
DNP-BM2-sds
DNP-BM2-elisa_1
DNP-FM1 Mouse FITC-Labeled Monoclonal Anti-DNP antibody, Mouse IgG1 Isotype Control (carrier free)
DNP-FM1-sds
DNP-FM2 Human FITC-Labeled Monoclonal Anti-DNP antibody, Human IgG1 Isotype Control (carrier free)
DNP-FM2-sds
DNP-BM1 Mouse Biotinylated Monoclonal Anti-DNP antibody, Mouse IgG1 Isotype Control (carrier free, MALS verified)
DNP-BM1-sds
DNP-BM1-elisa_1
DNP-MB273 Human Monoclonal Anti-DNP antibody, Human IgG1 (N297A) Isotype Control (carrier free, MALS verified)
DNP-MB273-sds
DNP-MB273-elisa_1
DNP-M3 Human Monoclonal Anti-DNP antibody, Human IgG4 Isotype Control (carrier free, MALS verified)
DNP-M3-sds
DNP-M3-elisa_1
DNP-M2 Human Monoclonal Anti-DNP antibody, Human IgG1 Isotype Control (carrier free, MALS verified)
DNP-M2-sds
DNP-M2-elisa_1
DNP-M1 Mouse Monoclonal Anti-DNP antibody, Mouse IgG1 Isotype Control (Carrier free, MALS verified)
DNP-M1-sds
DNP-M1-elisa_1

Part of Bioactivity data

DNP-PM1-Cell-based assay
FACS assay shows that recombinant Biotinylated FACS

5e5 of Anti-CD19 CAR-293 cells were stained with 100 μL of 1:50 dilution (2 μL stock solution in 100 μL FACS buffer) of PE-Labeled Monoclonal Anti-DNP antibody, Mouse IgG1 Isotype Control (Cat. No. DNP-PM1) and positive control (Cat. No. FM3-HPY53) respectively, and PE signal was used to evaluate the binding activity (QC tested).

DNP-PM1-Cell-based assay
FACS assay shows that recombinant Biotinylated FACS

5e5 of PBMCs were stained with a series of concentrations of PE-Labeled Monoclonal Anti-DNP antibody, Mouse IgG1 Isotype Control (Cat. No. DNP-PM1), and PE signal was used to evaluate the binding activity (QC tested).

DNP-BM2-ELISA
Biotinylated Monoclonal Anti-DNP antibody, Human IgG1 Isotype ControlBiotinylated Monoclonal Anti-DNP antibody, Human IgG1 Isotype Control (Cat. No. DNP-BM2) ELISA bioactivity

Immobilized DNP-Albumin Conjugate, Bovine at 10 μg/mL (100 μL/well) can bind Biotinylated Monoclonal Anti-DNP antibody, Human IgG1 Isotype Control (Cat. No. DNP-BM2) with a linear range of 1-20 ng/mL (QC tested).

DNP-BM2-MALS-HPLC
Biotinylated Monoclonal Anti-DNP antibody, Human IgG1 Isotype Control (Cat. No. ) MALS images

The purity of Biotinylated Monoclonal Anti-DNP antibody, Human IgG1 Isotype Control (Cat. No. DNP-BM2) is more than 95% and the molecular weight of this protein is around 155-175 kDa verified by SEC-MALS.

Synonym Name

DNP,Dinitrophenyl

Background

A hapten is a small molecule that can elicit an immune response only when conjugated with a large carrier such as a protein. Typical haptens include drugs, urushiol, quinone, steroids, etc. Peptides and non-protein antigens usually need conjugating to a carrier protein (such as BSA (bovine serum albumin) or KLH (keyhole limpet hemocyanin) to become good immunogens). Additionally, haptens should be administered with an adjuvant to ensure a high quality immune response. It is important that the hapten design (preserving greatly the chemical structure and spatial conformation of target compound), selection of the appropriate carrier protein and the conjugation method are key conditions for the desired specificity anti-hapten antibodies. We design anti-hapten antibodies based on the HaptenDB information.

Clinical and Translational Updates

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