CEACAM-8 Protein - ACROBiosystems

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CEACAM-8

Brief Information

Name:Non specific cross-reacting antigen 95
Target Synonym:CGM6,Carcinoembryonic Antigen Gene Family Member 6,CD66b Antigen,NCA-95,CD67,Non-specific cross-reacting antigen NCA-95,Carcinoembryonic antigen CGM6,CD66b,CEACAM8,Carcinoembryonic Antigen Related Cell Adhesion Molecule 8,Carcinoembryonic Antigen-Related

Number of Launched Drugs:1
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Approved


CE8-H82E9	Human	Biotinylated Human CEACAM-8 / CD66b Protein, His,Avitag™
CE8-H5224	Human	Human CEACAM-8 / CD66b Protein, His Tag

Cat. No.

Species

Product Description

Structure

Purity

Feature

CE8-H82E9

Human

Biotinylated Human CEACAM-8 / CD66b Protein, His,Avitag™

CE8-H5224

Human

Human CEACAM-8 / CD66b Protein, His Tag

Part of Bioactivity data

CE8-H5224-ELISA

Immobilized Human CEACAM-8, His Tag (Cat. No. CE8-H5224) at 5 μg/mL (100 μL/well) can bind Biotinylated Human CEACAM-6, His,Avitag (Cat. No. CE6-H82E7) with a linear range of 0.078-1.25 μg/mL (QC tested).

Protocol

CE8-H82E9-ELISA

Immobilized Human CEACAM-6, His Tag (Cat. No. CE6-H5223) at 10 μg/mL (100 μL/well) can bind Biotinylated Human CEACAM-8, His,Avitag (Cat. No. CE8-H82E9) with a linear range of 0.02-0.313 μg/mL (QC tested).

Protocol

Synonym Name

CEACAM8,CD66b,CD67,CGM6,NCA-95

Background

Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) is also known as CD66b (Cluster of Differentiation 66b), CD66b, CD67, CGM6, NCA-95, and is one of seven human CEACAM family members within the immunoglobulin superfamily. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM8 is a single chain, two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is an activation marker for human granulocytes.

Clinical and Translational Updates

Public Drug Information