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HBEGF

Brief Information

Name:Heparin-binding EGF-like growth factor
Target Synonym:Heparin-Binding EGF-Like Growth Factor,DTSF,DTS,DTR,HB-EGF,DT-R,Diphtheria toxin receptor,HBEGF,Heparin Binding EGF Like Growth Factor,Diphtheria Toxin Receptor (Heparin-Binding Epidermal Growth Factor-Like Growth Factor),Heparin-Binding Epidermal Growth
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Cat. No. Species Product Description Structure Purity Feature
HBF-H52H3 Human Human HBEGF Protein, His Tag
HBF-H52H3-structure
HBF-H52H3-sds
HBF-H52H3-elisa_1

Part of Bioactivity data

HBF-H52H3-ELISA
Human HBEGF, His TagHuman HBEGF, His Tag (Cat. No. HBF-H52H3) ELISA bioactivity

Immobilized Human HBEGF, His Tag (Cat. No. HBF-H52H3) at 5 μg/mL (100 μL/well) can bind Human EGF R, Fc Tag (Cat. No. EGR-H5252) with a linear range of 1-20 ng/mL (QC tested).

Synonym Name

HBEGF, HB-EGF, Heparin-binding EGF-like growth factor, Diphtheria toxin receptor, DT-R,  DTR, DTS, HEGFL

Background

Heparin-binding epidermal growth factor (EGF)-like growth factor (HBEGF) is a ligand for the EGF receptor (EGFR) and a critical molecular component to a number of normal physiological processes including but not limited to tissue injury and wound healing, reproduction, angiogenesis and recently, adipogenesis. Misexpression of HB-EGF is linked to tumor formation and cancer including hepatocellular, pancreatic, gastric, breast, colon and melanoma, gliomas and glioblastomas.

Clinical and Translational Updates

    Clinical Drug Information

    Name Research Code Research Phase Company Indications Clinical Trials
    ASP-0598 ASP-0598 Phase 2 Clinical Auration Biotech, Astellas Pharma Inc Ear Diseases; Tympanic Membrane Perforation Details

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