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Brief Information

Name:Heparin-binding EGF-like growth factor
Target Synonym:DTS,DTR,HB-EGF,DT-R,Diphtheria toxin receptor,HBEGF,Heparin Binding EGF Like Growth Factor,Diphtheria Toxin Receptor (Heparin-Binding Epidermal Growth Factor-Like Growth Factor),Heparin-Binding Epidermal Growth Factor,HEGFL,Proheparin-Binding EGF-Like Growth Factor,Heparin-Binding EGF-Like Growth Factor,DTSF,Diphtheria Toxin Receptor (Heparin-Binding EGF-Like Growth Factor)
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Discontinued

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Cat. No. Species Product Description Structure Purity Feature
HBF-H52H3 Human Human HBEGF Protein, His Tag
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Part of Bioactivity data


Immobilized Human HBEGF, His Tag (Cat. No. HBF-H52H3) at 5 μg/mL (100 μL/well) can bind Human EGF R, Fc Tag (Cat. No. EGR-H5252) with a linear range of 1-20 ng/mL (QC tested).

Synonym Name

HBEGF, HB-EGF, Heparin-binding EGF-like growth factor, Diphtheria toxin receptor, DT-R,  DTR, DTS, HEGFL


Heparin-binding epidermal growth factor (EGF)-like growth factor (HBEGF) is a ligand for the EGF receptor (EGFR) and a critical molecular component to a number of normal physiological processes including but not limited to tissue injury and wound healing, reproduction, angiogenesis and recently, adipogenesis. Misexpression of HB-EGF is linked to tumor formation and cancer including hepatocellular, pancreatic, gastric, breast, colon and melanoma, gliomas and glioblastomas.

Clinical and Translational Updates

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