Name:Toll like receptor 2 Target Synonym:CD282,Toll-like receptor 2,TIL4,Toll/interleukin-1 receptor-like protein 4,TLR2,Toll Like Receptor 2,CD282 Antigen,EC:3.2.2.6
Number of Launched Drugs:1 Number of Drugs in Clinical Trials:5 Lastest Research Phase:Phase 2 Clinical
Synonym Name
Background
Toll-like receptors (TLRs) take key roles in the host immune response and are swiftly activated by infection or other types of immunological stress. Toll-like receptor 2 (TLR2) is indicated to initiate the activation of NLRP3 inflammasome and might involve in asthma. Additionally, further research uncovered that Wnt5a is also a direct ligand of toll-like receptor (TLR) 2 and 4 might affect the typical pattern recognition receptor-induced innate immune response genes.
Clinical and Translational Updates
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