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Your Position: Home > TLR8

TLR8

Brief Information

Name:Toll like receptor 8
Target Synonym:UNQ249/PRO286,TLR8,Toll-like receptor 8,CD288,Toll Like Receptor 8,CD288 Antigen
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:12
Lastest Research Phase:Phase 2 Clinical

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Synonym Name

TLR8/CD288/Toll-like receptor 8

Background

Toll-like receptors (TLRs) sense pathogen-associated molecular patterns originating from invading microorganisms and initiate innate immune responses. Toll-like receptors 8 and 7 (TLR8 and TLR7) are endosomal immune receptors and take a key role in innate and adaptive immunity. As a transmembrane receptor, TLR8 could recognize single-stranded RNA. Activation of TLR8 and TLR7 lead to immune cell stimulation and inflammatory cytokine production, which is normally a protective host response.

Clinical and Translational Updates

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