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Your Position: Home > CCL5

CCL5

Brief Information

Name:C-C motif chemokine 5
Target Synonym:T-Cell Specific RANTES Protein,Chemokine CXCL5,T-Cell Specific Protein P288,Beta-Chemokine RANTES,T-Cell-Specific Protein RANTES,SCYA5,Eosinophil Chemotactic Cytokine,Small Inducible Cytokine Subfamily A (Cys-Cys), Member 5,C-C Motif Chemokine Ligand 5,Eo
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 2 Clinical

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Cat. No. Species Product Description Structure Purity Feature
CC5-H5251 Human Human CCL5/RANTES Protein, Fc Tag (MALS verified)
CC5-H5251-structure
CC5-H5251-sds

Part of Bioactivity data

CC5-H5251-ELISA
Human CCL5, Fc Tag (Cat. No. ) MALS images

The purity of Human CCL5, Fc Tag (Cat. No. CC5-H5251) was more than 90% and the molecular weight of this protein is around 65-75 kDa verified by SEC-MALS.

Report
  • Background
    C-C chemokine ligand 5 (CCL5), also known as RANTES, is a target gene of NF-kappaB, and is expressed by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumour cells. CCL5 plays a role in recruiting a variety of leukocytes into inflammatory sites including T cells, macrophages, eosinophils, and basophils. CCL5 activity is mediated through its binding to CCR1, CCR3, and mainly CCR5.
  • Clinical and Translational Updates
      

  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

Synonym Name

EoCP,Eosinophil chemotactic cytokine,SIS-delta,Small-inducible cytokine A5,T cell-specific protein P228,TCP228,D17S136E, SCYA5,CCL5,C-C motif chemokine 5T-cell-specific protein RANTES

Background

C-C chemokine ligand 5 (CCL5), also known as RANTES, is a target gene of NF-kappaB, and is expressed by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumour cells. CCL5 plays a role in recruiting a variety of leukocytes into inflammatory sites including T cells, macrophages, eosinophils, and basophils. CCL5 activity is mediated through its binding to CCR1, CCR3, and mainly CCR5.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
NI-0701 NI-0701 Phase 1 Clinical Novimmune Autoimmune Diseases Details
AFX-5931 AFX-5931 Phase 2 Clinical Afecta Pharmaceutical Eczema Details

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