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FOLR3

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Cat. No. Species Product Description Structure Purity Feature
FO3-H52H3 Human Human FOLR3 Protein, His Tag (MALS verified)
FO3-H52H3-structure
FO3-H52H3-sds
FO3-H52H3-elisa_2

Part of Bioactivity data

FO3-H52H3-SPR
Human_FcRn_Heterodimer_Protein_SPR

Folic acid-BSA immobilized on CM5 Chip can bind Human FOLR3, His Tag (Cat. No. FO3-H52H3) with an affinity constant of 1.03 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

FO3-H52H3-MALS-HPLC
Human FOLR3, His Tag (Cat. No. ) MALS images

The purity of Human FOLR3, His Tag (Cat. No. FO3-H52H3) was more than 90% and the molecular weight of this protein is around 28-42 kDa verified by SEC-MALS.

Bioactivity-SPR
Human_FcRn_Heterodimer_Protein_SPR

Folic acid-BSA immobilized on CM5 Chip can bind Human FOLR3, His Tag (Cat. No. FO3-H52H3) with an affinity constant of 1.03 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

Synonym Name

folate receptor 3 (gamma),Folate receptor 3,folate receptor gamma,FOLR3,FR-G,FR-gamma,gamma-Hfr,

Background

FOLR3, also know as folate receptor gamma, is a member of FRs. Folic acid and its reduced derivatives are transported via two widely expressed transporters, the reduced folate carrier (RFC) and the proton-coupled folate transporter (PCFT), and via a family of glycosyl-phosphatidylinositol (GPI)-anchored receptors with limited expression profiles known as folate receptors (FRs).Folate receptors (FR) are high affinity receptors that transport folate via endocytosis. Human FR exists in three isoforms, alpha and beta equipped with GPI anchors, and gamma not possessing a GPI anchor.

Clinical and Translational Updates

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