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Your Position: Home > CCL3

CCL3

Brief Information

Name:Macrophage inflammatory protein 1-α
Target Synonym:CCL3,PAT 464.1,C-C Motif Chemokine 3,Macrophage inflammatory protein 1-alpha,G0S19-1,C-C Motif Chemokine Ligand 3,Small Inducible Cytokine A3 (Homologous To Mouse Mip-1a),Tonsillar Lymphocyte LD78 Alpha Protein,Chemokine (C-C Motif) Ligand 3,MIP-1-Alpha,SIS-Beta,LD78ALPHA,Chemokine CCL3,G0/G1 switch regulatory protein 19-1,Small-inducible cytokine A3,SCYA3,LD78-alpha(4-69),MIP1A
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Pending

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By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
CC3-H5249 Human Human CCL3 / MIP-1 alpha Protein, His Tag
CC3-H5249-structure
CC3-H5249-sds

Synonym Name

C-C motif chemokine 3,MIP1-(a),AI323804,CCL3,chemokine (C-C motif) ligand 3,G0S19-1,LD78a,LD78alpha,MIP1 alpha,MIP-1 alpha,MIP1A,MIP-1alpha,MIP1-alpha

Background

CCL3, also know as MIP-1-alpha, is monokine with inflammatory and chemokinetic properties. CCL3 is an important chemokine implicated in both immune surveillance and tolerance, has emerged as a prognostic biomarker in both solid and hematological malignancies. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

Clinical and Translational Updates

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