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Cadherin-6

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Part of Bioactivity data

CA6-C52H3-ELISA
Cynomolgus / Rhesus macaque Cadherin-6, His TagCynomolgus / Rhesus macaque Cadherin-6, His Tag (Cat. No. CA6-C52H3) ELISA bioactivity

Immobilized Cynomolgus / Rhesus macaque Cadherin-6, His Tag (Cat. No. CA6-C52H3) at 1 μg/mL (100 μL/well) can bind Human Cadherin-6 Antibody, Mouse IgG1 with a linear range of 0.1-1 ng/mL (QC tested).

CA6-H5258-MALS-HPLC
Human Cadherin-6 Protein, Fc Tag (Cat. No. ) MALS images

The purity of Human Cadherin-6 Protein, Fc Tag (Cat. No. CA6-H5258) is more than 90% and the molecular weight of this protein is around 200-240 kDa verified by SEC-MALS.

Bioactivity-ELISA
Human Cadherin-6 Protein, Fc TagHuman Cadherin-6 Protein, Fc Tag (Cat. No. CA6-H5258) ELISA bioactivity

Immobilized Human Cadherin-6 Protein, Fc Tag (Cat. No. CA6-H5258) at 1 μg/mL (100 μL/well) can bind Human Cadherin-6 Antibody, Mouse IgG1 with a linear range of 0.1-1 ng/mL (QC tested).

Synonym Name

CDH6,CAD6,KCAD,K-cadherin,Cadherin-6

Background

Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a  a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.

Clinical and Translational Updates

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