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Your Position: Home > MAOA

MAOA

Brief Information

Name:Monoamine oxidase A
Target Synonym:EC 1.4.3,EC:1.4.3.4,Monoamine oxidase type A,Amine Oxidase [Flavin-Containing] A,MAO-A,MAOA,Monoamine Oxidase A,EC 1.4.3.4,BRNRS
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
MAA-M5548 Mouse Mouse MAOA Protein, His Tag
MAA-M5548-structure
MAA-H5547 Human Human MAOA Protein, His Tag (active enzyme)
MAA-H5547-structure
MAA-H5547-sds
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Synonym Name

MAO-A,Monoamine Oxidase A

Background

MAOA, Monoamine oxidase-A is an FAD-dependent mitochondrial enzyme, which, together with its isoenzyme MAO-B, catalyses the oxidative deamination of structurally diverse amines. MAOA is mainly involved in the metabolism of monoamine neurotransmitters, such as such as serotonin, dopamine, and norepinephrine. Inhibitors of MAOA are in clinical use for affective disorders and is approved to treat despression.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Toloxatone MD-69276 Approved Umoril, Humoryl, Perenum France Depression null 1984-01-01 Depression Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
CB-2202 CB-2202 Phase 2 Clinical Cennerv Pharma Depressive Disorder, Major Details
Ladostigil TV-3326 Teva Details

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