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CXCL1

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Cat. No. Species Product Description Structure Purity Feature
CX1-H5253 Human Human CXCL1 Protein, Fc Tag (MALS verified)
CX1-H5253-structure
CX1-H5253-sds
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Part of Bioactivity data

CX1-H5253-ELISA
CXCL1 MALS images

The purity of Human CXCL1, Fc Tag (Cat. No. CX1-H5253) is more than 95% and the molecular weight of this protein is around 60-75 kDa verified by SEC-MALS.

Synonym Name

Growth-regulated alpha protein, C-X-C motif chemokine 1, GRO-alpha, Melanoma growth stimulatory activity, MGSA, Neutrophil-activating protein 3, NAP-3, GRO1, SCYB1

Background

Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small molecule of cytokines belonging to the CXC chemokine family. Also known as growth-regulated oncogene alpha (Growth-regulated oncogene alpha, GROα). It's also known as keratinocytes-derived chemokine (KC) in mice or cytokine-induced neutrophil chemoattractant type-1 (CINC-1) in rats. In humans, this protein is encoded by the gene Cxcl1 and is located on human chromosome 4 among genes for other CXC chemokines. The chemokine CXCL1 is expressed by macrophages, neutrophils and epithelial cells. The chemokine CXCL1 has a chemotactic effect on neutrophils. CXCL1 binds to the chemokine receptor CXCR2 and plays a role in cell chemotaxis. Human CXCL1 is clustered on chromosome 4 adjacent to many CXC chemokine genes. Major roles of CXCL1 include neovascularization, inflammation, wound healing, and tumorigenesis

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