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Your Position: Home > Plectin

Plectin

Brief Information

Name:Plectin
Target Synonym:PLTN,Hemidesmosomal protein 1
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Cat. No. Species Product Description Structure Purity Feature
PLN-H5249 Human Human Plectin / PLTN Protein, His Tag
PLN-H5249-structure
PLN-H5249-sds
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Synonym Name

Plectin,PLTN,PCN,HD1,Hemidesmosomal protein 1,PLEC1

Background

Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Ibentatug ZB-131 Phase 2 Clinical Zielbio Inc Solid tumours; Biliary Tract Neoplasms; Ovarian Neoplasms; Cystadenocarcinoma, Serous; Carcinoma, Pancreatic Ductal Details

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