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Brief Information

Name:Protease-activated receptor-1
Target Synonym:Coagulation Factor II (Thrombin) Receptor,Proteinase-Activated Receptor 1,Coagulation Factor II Receptor,Protease-Activated Receptor 1,Protease Activated Receptor 1,Thrombin Receptor,HTR,Receptor, PAR-1,PAR1,F2R,Coagulation Factor II Thrombin Receptor,PAR-1,CF2R,TR
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
PA1-HF2G5 Human Fluorescent Human PAR1 Full Length Protein (VLP)
PA1-H52P6 Human Human PAR1 Full Length Protein (VLP)
ACRO Quality

Part of Bioactivity data


Immobilized Human PAR1 Full Length Protein-VLP (Cat. No. PA1-H52P6) at 5 μg/mL (100 μL/well) can bind Monoclonal Anti-Human PAR1 antibody, Mouse IgG1 with a linear range of 0.1-1.3 μg/mL (QC tested).


Immobilized Fluorescent Human PAR1 Full Length Protein (VLP) (Cat. No. PA1-HF2G5) at 5 μg/mL (100 μL/well) can bind Monoclonal Anti-PAR1 Antibody (Mouse IgG) with a linear range of 0.6-10 ng/mL (QC tested).

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Vorapaxar Sulfate MK-5348; TRA-SCH-530348; SCH-530348 Approved Merck Sharp & Dohme Corp Zontivity United States Coronary Thrombosis; Myocardial Infarction; Peripheral Arterial Disease; Thrombosis Xspire Pharma 2014-05-08 Myocardial Ischemia; Myocardial Infarction; Atherosclerosis; Arterial Occlusive Diseases; Stroke; Acute Coronary Syndrome; Coronary Thrombosis; Coronary Disease; Arteriovenous Fistula; Ischemia; Peripheral Arterial Disease; Thrombosis; Cerebral Infarction Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
PZ-128 PZ-128 Phase 2 Clinical Tufts Medical Center Inc Myocardial Ischemia; Arterial Occlusive Diseases; Heart Diseases; Coronary Artery Disease; Acute Coronary Syndrome; Vascular Diseases; Coronary Disease; Arteriosclerosis Details
Rusalatide TRAP-508; TP-508 Phase 1 Clinical Baylor College Of Medicine, University Of Texas Medical Branch Respiratory Distress Syndrome, Adult; Radius Fractures Details

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