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Your Position: Home > TROP2

TROP2

Brief Information

Name:Tumor-associated calcium signal transducer 2
Target Synonym:Tumor-associated calcium signal transducer 2,M1S1,TROP2,TACSTD2,Pancreatic carcinoma marker protein GA733-1,Tumor Associated Calcium Signal Transducer 2,GA733-1,Membrane Component, Chromosome 1, Surface Marker 1,Gastrointestinal Tumor-Associated Antigen GA7331,Pancreatic Carcinoma Marker Protein GA7331,Cell surface glycoprotein Trop-2,Membrane component chromosome 1 surface marker 1,40kD Glycoprotein, Identified By Monoclonal Antibody GA733,Cell Surface Glycoprotein TROP2,Epithelial Glycoprotein
Number of Launched Drugs:3
Number of Drugs in Clinical Trials:25
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
HCS-S310 Mouse Recombinant Monoclonal Anti-TROP2 Antibody, Mouse (2A9)
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Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Sacituzumab govitecan IMMU-132; TROP-2-SN-38; IMMU0132; GS-0132; IMMU-0132 Approved Immunomedics Inc, Gilead Sciences Inc Trodelvy, 拓达维, TRODELVY United States Triple Negative Breast Neoplasms Immunomedics Inc 2020-04-22 Brain metastases; Mesothelioma; Urinary Bladder Neoplasms; Klatskin Tumor; Breast Neoplasms; Cholangiocarcinoma; Prostatic Neoplasms; Bile Duct Neoplasms; Metastatic breast cancer; Hormone-Resistant Prostate Neoplasms; Thymoma; Esophageal Squamous Cell Carcinoma; Endometrial Neoplasms; Thyroid Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Solid tumours; Thyroid Carcinoma, Anaplastic; Salivary Gland Neoplasms; Carcinoma, Ovarian Epithelial; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Triple Negative Breast Neoplasms; Glioblastoma; Carcinoma, Transitional Cell; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Esophageal Neoplasms; Biliary Tract Neoplasms; Ovarian Neoplasms; Liver Failure Details
Datopotamab deruxtecan DS-1062a; DS-1062; Dato-DXd; S-1062a Approved Daiichi Sankyo Co Ltd Datroway, DATROWAY Japan Breast Neoplasms Daiichi Sankyo Co Ltd 2024-12-27 Solid tumours; Biliary Tract Neoplasms; Ovarian Neoplasms; Carcinoma; Stomach Neoplasms; Triple Negative Breast Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Endometrial Neoplasms; Metastatic breast cancer; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
Sacituzumab tirumotecan SKB-264; MK-2870; SKB264; sac-TMT Approved Klus Pharma Inc 佳泰莱 Mainland China Triple Negative Breast Neoplasms Sichuan Kelun-Biotech Biopharmaceutical Co Ltd 2024-11-22 Triple Negative Breast Neoplasms; Gastrointestinal Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Metastatic breast cancer; Carcinoma, Pancreatic Ductal; Endometrial Neoplasms; Colorectal Neoplasms; Breast Neoplasms; Urinary Bladder Neoplasms; Biliary Tract Neoplasms; Carcinoma, Transitional Cell; Small Cell Lung Carcinoma; Carcinoma, Ovarian Epithelial; Carcinoma; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Solid tumours Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
SHR-A1921 SHR-A1921; SHRA1921; SHR-1921 Phase 3 Clinical Suzhou Suncadia Biopharmaceuticals Co Ltd, Shanghai Hengrui Pharmaceutical Co Ltd Solid tumours; Ovarian Neoplasms; Carcinoma, Ovarian Epithelial; Triple Negative Breast Neoplasms; Salivary Gland Neoplasms; Neoplasms; Breast Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Metastatic breast cancer; Brain metastases; Carcinoma, Non-Small-Cell Lung Details
ESG-401 STI-3258; OQY-3258; ESG-401 Phase 3 Clinical Shanghai Escugen Biotechnology Co Ltd Ovarian Neoplasms; Solid tumours; Stomach Neoplasms; Triple Negative Breast Neoplasms; Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Metastatic breast cancer Details
FDA018 Antibody Drug Conjugate FDA018-ADC; FDA-018-ADC Phase 3 Clinical Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd Solid tumours; Neoplasms; Triple Negative Breast Neoplasms; Breast Neoplasms Details
GQ-1010 GQ-1010; BHV1510; BHV-1510; GQ1010; PBI-410 Phase 2 Clinical GeneQuantum Healthcare (Suzhou) Co Ltd Solid tumours; Carcinoma; Triple Negative Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Trop2 CAR-NK cell therapy(Henan Provincial Cancer Hospital) Phase 2 Clinical Henan Provincial Cancer Hospital Carcinoma, Non-Small-Cell Lung Details
OBI-992 BSI-992; BSI992; R-992; OBI-992 Phase 2 Clinical Boaoxin Biotechnology(Nanjing) Co Ltd Solid tumours; Stomach Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Non-Small-Cell Lung Details
JSKN-016 JSKN016; JSKN-016 Phase 2 Clinical Jiangsu Alphamab Biopharmaceuticals Co Ltd Solid tumours; Neoplasms; Carcinoma, Non-Small-Cell Lung Details
HS-20105 HS-20105; HS20105 Phase 2 Clinical Hansoh BioMedical R&D Company Solid tumours Details
IBI130 IBI130; IBI-130 Phase 2 Clinical Innovent Biologics(Suzhou) Co Ltd Solid tumours; Neoplasm Metastasis Details
Anti TROP2 antibody drug conjugate ADC（Fudan University） Phase 2 Clinical Fudan University Triple Negative Breast Neoplasms Details
9MW-2921 9MW2921; 9MW-2921 Phase 2 Clinical Mabwell (Shanghai) Bioscience Co Ltd Solid tumours Details
MHB036C MHB-036C Phase 2 Clinical Minghui Pharmaceutical Pty Ltd Solid tumours; Lung Neoplasms Details
BAT-8008 BAT-8008; BAT8008 Phase 2 Clinical Bio-Thera Solutions Ltd Solid tumours; Triple Negative Breast Neoplasms Details
DB-1305 DB1305; BNT325; BNT-325; DB-1305 Phase 2 Clinical Duality Biologics (Suzhou) Co Ltd Solid tumours Details
BIO-106 BIO-106 Phase 2 Clinical Hangzhou Baikai Biopharmaceutical Co Ltd Solid tumours; Neoplasms Details
BL-M02D1 Phase 2 Clinical Baili-Bio (Chengdu) Pharmaceutical Co Ltd, Sichuan Baili Pharmaceutical Co Ltd Solid tumours; Triple Negative Breast Neoplasms; Digestive System Neoplasms; Breast Neoplasms; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
LCB-84 LCB-84 Phase 2 Clinical Legochem Biosciences Inc Solid tumours Details
JS-108 DAC-002; JS-108; DAC-002/JS108 Phase 1 Clinical Hangzhou Dac Biotech Company Ltd Solid tumours; Small Cell Lung Carcinoma; Triple Negative Breast Neoplasms Details
IBR-822 IBR822; IBR-822 Phase 1 Clinical Imbioray (Hangzhou) Biomedicine Co Ltd Solid tumours Details
DXC-1002 DXC1002; DXC-1002 Phase 1 Clinical Hangzhou Dac Biotech Company Ltd Solid tumours Details
DS-001 DS001; DS-001 Phase 1 Clinical Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Dartsbio Pharmaceuticals Ltd Neoplasms Details
FZ-AD004 FZ-AD004 Phase 1 Clinical Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd Solid tumours Details
BCG-011 DM-001; BCG-011 Phase 1 Clinical Biocytogen Pharmaceuticals (Beijing) Co Ltd Solid tumours; Triple Negative Breast Neoplasms; Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details
MT-302 MT-302 Phase 1 Clinical Myeloid Therapeutics Inc Carcinoma; Colonic Neoplasms; Breast Neoplasms; Lung Neoplasms Details

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