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Ephrin-A3

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Cat. No. Species Product Description Structure Purity Feature
EA3-H5258 Human Human Ephrin-A3 / EFNA3 Protein, Fc Tag
EA3-H5258-structure
EA3-H5258-sds
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Part of Bioactivity data

EA3-H5258-MALS-HPLC
 Ephrin-A3 ELISA

Immobilized Human EphA10, His Tag (Cat. No. EP0-H52H3) at 5 μg/mL (100 μL/well) can bind Human Ephrin-A3, Fc Tag (Cat. No. EA3-H5258) with a linear range of 0.1-2 ng/mL (Routinely tested).

Synonym Name

Ephrin-A3,EFL-2,EHK1-L,LERK-3,EFNA3

Background

Ephrin-A3 (Ephrin A3) is also known as EFL-2, EHK1 ligand, EHK1-L, EPH-related receptor tyrosine kinase ligand 3, EFL2, EPLG3 and LERK3,which comprises the largest subfamily of receptor protein-tyrosine kinases (RTKs), and has been involved in a variety of biological processes, especially in the nervous system and in erythropoiesis, such as axon guidance and topographic map formation, synaptic plasticity, angiogenesis, and meanwhile have possible contributions to tumor growth and metastasis. Ephrin A3 is cell surface GPI-bound ligand for Eph receptors and belongs to the family of receptor tyrosine kinases. Ephrin can bind promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.

Clinical and Translational Updates

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