Ephrin-A4 Protein - ACROBiosystems

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Ephrin-A4

Brief Information

Name:Ephrin-A4
Target Synonym:LERK-4,Ephrin-A4,EPH-Related Receptor Tyrosine Kinase Ligand 4,EPLG4,Ephrin A4,LERK4,EFNA4,Ligand Of Eph-Related Kinase 4,EFL4

Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Discontinued


EA4-H5229	Human	Human Ephrin-A4 / EFNA4 Protein, His Tag
EA4-H5250	Human	Human Ephrin-A4 / EFNA4 Protein, Fc Tag

Cat. No.

Species

Product Description

Structure

Purity

Feature

EA4-H5229

Human

Human Ephrin-A4 / EFNA4 Protein, His Tag

EA4-H5250

Human

Human Ephrin-A4 / EFNA4 Protein, Fc Tag

Part of Bioactivity data

EA4-H5250-MALS-HPLC

Human Ephrin-A4, Fc TagHuman Ephrin-A4, Fc Tag (Cat. No. EA4-H5250) ELISA bioactivity

Immobilized Human EphA4, His Tag (Cat. No. EP4-H52H8) at 5 μg/mL (100 μL/well) can bind Human Ephrin-A4, Fc Tag (Cat. No. EA4-H5250) with a linear range of 0.6-5 ng/mL (QC tested).

Protocol

Synonym Name

EFNA4,EPLG4,LERK4,Ephrin-A4

Background

Ephrin-A4 (EFNA4) is also known as EPH-related receptor tyrosine kinase ligand 4 (LERK4), EPLG4, which belongs to the ephrin family. EFNA4 contains one ephrin RBD (ephrin receptor-binding) domain. EFNA4 is cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. EFNA4 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. EFNA4 may play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.

Clinical and Translational Updates