Ephrin-B1
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Ephrin-B1 Molecule Synonym Name
EFNB1,EFL-3,ELK ligand,ELK-L,EPLG2,LERK2,CFND,CFNS
Ephrin-B1 Molecule Background
Ephrin-B1 (EFNB1) is also known as EFL-3, ELK ligand, EPH-related receptor tyrosine kinase ligand 2 (LERK-2), which belongs to the ephrin family. EFNB1 contains one ephrin RBD (ephrin receptor-binding) domain. EFNB1 binds to the receptor tyrosine kinases EPHB1 and EPHA1. EFNB1 binds to, and induce the collapse of, commissural axons/growth cones in vitro. EFNB1 may play a role in constraining the orientation of longitudinally projecting axons. EFNB1 interacts with GRIP1 and GRIP2.
Ephrin-B1 References