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Frizzled-5

Frizzled-5 Protein Product ListCompare or Buy

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Cat. No. Species Product Description Structure Purity Feature
FZ5-H5259 Human Human Frizzled-5 / FZD5 Protein, Fc Tag
FZ5-H5259-structure
FZ5-H5259-sds

Frizzled-5 Molecule Synonym Name

FZD5,Frizzled-5,C2orf31,,Fz-5,hFz5,FzE5

Frizzled-5 Molecule Background

Frizzled-5 (FZD5) is also known as FzE5, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD5 contains one FZ (frizzled) domain. FZD5 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD5 interacts specifically with Wnt5A to induce the beta-catenin pathway. FZD5 interacts with GOPC.

Frizzled-5 References

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