HSP90AA1 Molecule Information
Name:Heat shock protein HSP 90-alpha
Target Synonym:HSP90A ;HSPCA;Heat shock 86 kDa;HSP86;Renal carcinoma antigen NY-REN-38;Lipopolysaccharide-associated protein 2;LPS-associated protein 2;LAP-2;HSP90AA1;HSPC1;Heat shock protein HSP 90-alpha;HSP 86
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase ?
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HSP90AA1 Molecule Synonym Name
HSP90AA1 Molecule Background
Heat shock protein HSP 90-alpha (HSP90AA1 or HSP90A) is also known as Heat shock 86 kDa (HSP 86 or HSP86), Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, which belongs to the heat shock protein 90 family. HSP90AA1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. HSP90AA1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
HSP90AA1 Clinical Drug Information
||Taiho Pharma, Otsuka
||Gastrointestinal stromal tumors (GISTs)