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IL-13 R alpha 1

IL-13 R alpha 1 Product List

Cat. No. Species Product Description Structure Purity Feature
IL1-H5224 Human Human IL-13 R alpha 1 Protein
IL1-H9224 Human Human IL-13 R alpha 1 Protein, C13 and N15-labeled
IL1-M52H7 Mouse Mouse IL-13 R alpha 1 Protein
IL1-M5258 Mouse Mouse IL-13 R alpha 1 Protein, Fc Tag

IL-13 R alpha 1 Molecule Synonym Name


IL-13 R alpha 1 Molecule Background

Interleukin 13 receptor, alpha 1 is also known as IL13RA1, NR4 and CD213A1 (cluster of differentiation 213A1), The IL13 R¦Á1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. Human and mouseIL13R¦Á1 share 76% aa sequence identity. IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

IL-13 R alpha 1 References

IL-13 R alpha 1 Related Molecule

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